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Arthur Konnerth1
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Arthur Konnerth1
Stefan Lichtenthaler27
Stephan Müller26
Christian Behrends17
Mikael Simons11
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Martina Schifferer6
Rainer Malik5
Özgün Gökçe5
Thomas Misgeld4
Christian Haass3
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Bernhard Hemmer1
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Matthias Brendel1
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Wolfgang Wurst1
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Mitochondria vary in morphology and function in different tissues, however little is known about their molecular diversity among cell types. To investigate mitochondrial diversity in vivo, we developed an efficient protocol to isolate cell type-specific mitochondria based on a new MitoTag mouse. We profiled the mitochondrial proteome of three major neural cell types in cerebellum and identified a substantial number of differential mitochondrial markers for these cell types in mice and humans. ...