Data files

CUT&tag sequencing of mouse BM monocytes and HSPC-enriched myeloid cells from mice one month after stroke or control conditions was performed

Bulk mRNA sequencing of human heart paraffin embeded samples from stroke patients and control patients

Bulk ATAC sequencing of mouse HSPC-enriched BM cells treated with recombinant IL-1b or vehicle

Mouse single-nuclei ATAC experiment performed on myeloid cells from bone marrow chronically after stroke and control conditions. An additional group of bone marrow cells from stroke mice treated with neutralizing antibodies against IL-1b was also included (stroke-treated group).

A single-cell RNA experiment was performed on cardiac interstitial cells from mice one month after stroke or control conditions

A single-cell RNA experiment was performed on bone marrow myeloid progenitor and mature cells chronically after stroke

A single-cell RNA experiment was performed on blood and heart myeloid cells from BM-depleted recipient mice that were transplanted with bone marrow cells from stroke or control donors.