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Created At
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Submitter
Rainer Malik1
Project
SyNergy - published datasets1
Creator
Arthur Liesz1
Assay type
Transcriptomics1
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Technology Type1
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The crosstalk between brain infiltrating T cells and microglia in response to stroke remains elusive. Benakis et al. report that transcriptional signature of the stroke-associated microglia is reprogrammed by distinct T cell subpopulations. Engineered T cells overexpressing IL-10 administered four hours after stroke reinitiate microglial transcriptomic profile inducing a pro-regenerative environment.
Creator: Arthur Liesz
Submitter: Rainer Malik
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